Adipose-PRP Ovarian Rejuvenation

Standard PRP is typically the first-line approach. Your doctor may recommend upgrading to Adipose-PRP if you are over 45, if your AMH is extremely low or zero, if you've already tried standard PRP without adequate response, or if you've had multiple failed IVF cycles with poor egg quality. Adipose-PRP adds fat-derived stem cells to create a stronger regenerative signal — it's designed for cases where platelets alone may not be enough. Your physician at RFC will assess your history and recommend the right starting point.

No. Adipose-PRP ovarian rejuvenation is not FDA approved as a fertility treatment. It is an autologous procedure using your own blood and fat tissue, which falls under the practice of medicine rather than drug or device regulation. PRP and adipose stem cell therapies are used across many medical fields under this same framework. While published evidence — including the first documented live births in women over 45 — is encouraging, larger randomized controlled trials are still ongoing. RFC provides full informed consent and transparent counseling before any procedure.

A failed PRP at another clinic does not mean regenerative treatment won't work for you. PRP outcomes depend heavily on platelet concentration, injection technique, needle size, injection sites, and post-procedure protocol — all of which vary between providers. Adipose-PRP adds fat-derived stem cells that provide a stronger biological stimulus than PRP alone. RFC will review your prior treatment details, current hormone levels, and IVF history to determine whether Adipose-PRP is the right next step or whether other options should be explored.

Adipose-PRP may produce a longer response window than standard PRP due to the regenerative potential of fat-derived stem cells, but exact duration varies by individual. Because the effects are temporary and ovarian aging continues, patients who show improvement are encouraged to proceed with IVF, egg freezing, or natural conception without delay. Your physician will use weekly monitoring to identify the optimal timing for treatment — waiting too long risks losing the response window.

The mini-liposuction used in Adipose-PRP is very small — fat is collected through a tiny abdominal entry point, typically less than 1 cm. Most patients have no visible scarring once healed. Recovery is quick: mild soreness at the collection site for 1 to 2 days, and most patients return to normal activities within 24 to 48 hours. The procedure is performed under anesthesia with comfort measures and takes approximately 30 minutes as part of the overall 2-hour appointment.

Some patients may be able to conceive naturally after Adipose-PRP if ovarian function improves, the fallopian tubes are open, and there are no significant male fertility factors. However, most patients — especially those over 40 or with severely diminished ovarian reserve — are advised to pursue IVF or egg freezing to maximize the response window. RFC offers three types of IVF, including natural and mini approaches, and does not recommend aggressive high-dose stimulation after rejuvenation. Your physician will guide the best path based on your monitoring results.