Here’s what your doctor may have missed:

1️⃣ It might not be an egg or sperm issue at all — it could be IMPLANTATION. Meet “Endometrial Insufficiency”
Shockingly, nearly 40% of patients doing IVF don’t actually need IVF. Sometimes, the embryo just can’t implant — and if no one checks the uterine environment, it’s easy to miss.

Endometrial insufficiency refers to a condition where the endometrium—the inner lining of the uterus—is too thin, poorly developed, or not optimally receptive to allow for proper implantation of an embryo.

Key Characteristics:

• Poor blood flow to the uterine lining.
• Impaired receptivity, meaning the lining may not respond well to hormonal signals that support embryo implantation.
• Thin endometrium: Often defined as <7 mm in thickness during the implantation window.

Causes:

• Hormonal imbalances (especially low estrogen)
• Previous uterine surgeries or infections (e.g., D&C, Asherman’s syndrome)
• Chronic inflammation (e.g., chronic endometritis)
• Prolonged use of certain fertility drugs
• Age-related decline in uterine function

Why it matters:

A healthy, receptive endometrium is essential for successful pregnancy, especially in fertility treatments like IVF. Endometrial insufficiency can lead to:

• Failed implantation
• Recurrent pregnancy loss
• Lower success rates with IVF and embryo transfer

Common treatments:

• Hysteroscopic evaluation and treatment of scarring or adhesions
• Vaginal Viagra (sildenafil) to improve blood flow
• Intrauterine PRP (platelet-rich plasma) infusions and/or PRP INJECTIONS BY HYSTEROSCOPY
• G-CSF (granulocyte colony-stimulating factor) infusions
• Lifestyle changes (nutrition, exercise, stress management)

2️⃣ We’re living in an increasingly INFLAMMATORY world. (see Reproductive Immunology section below)
Immune-related fertility issues are on the rise — and standard fertility clinics rarely test for them. That’s why we offer a comprehensive Reproductive Immunology Panel to identify immune imbalances that can block conception or cause miscarriage.

3️⃣ Sperm health goes far beyond a semen analysis.
Even when counts and motility look “normal,” Sperm DNA Fragmentation can cause infertility and miscarriage — and yes, it’s backed by the American Society for Reproductive Medicine (ASRM).

4️⃣ Hormonal Imbalances

• Subtle imbalances (like high prolactin, low progesterone, or thyroid dysfunction) may not be flagged in routine tests.
• Can affect ovulation, uterine lining, or early embryo support.

5️⃣ Lifestyle & Environmental Factors.
High stress, poor sleep, endocrine disruptors (plastics, pesticides), and toxins can impair fertility subtly but significantly.